{"id":50107,"date":"2021-08-04T19:33:08","date_gmt":"2021-08-04T19:33:08","guid":{"rendered":"https:\/\/www.moraeslab.com\/biapt\/?p=50107"},"modified":"2021-08-23T14:33:53","modified_gmt":"2021-08-23T14:33:53","slug":"event-related-potentials","status":"publish","type":"post","link":"https:\/\/www.moraeslab.com\/biapt\/event-related-potentials\/","title":{"rendered":"Event-Related Potentials"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Auditory event-related potentials (ERPs) have often been used to assess the level of consciousness of behaviourally unresponsive individuals.\u00a0 In this set of research projects, we first published a retrospective commentary of the critical factors to be considered when designing paradigms to evoke ERPs in patients in a disorder of consciousness.\u00a0 We demonstrated that 1) the ERP paradigm needs to account for the participant\u2019s age; 2) paradigm strength affects the characteristics of the resulting ERP; and 3) presentation speed needs to be adjusted for patients with potential cognitive impairments.\u00a0 Accounting for these factors enables us to design an ERP paradigm with the highest likelihood to evoke an ERP response in a patient with covert consciousness.\u00a0 The full study results are published in <\/span><i><span style=\"font-weight: 400;\">Brain Sciences<\/span><\/i><span style=\"font-weight: 400;\">: \u201c<\/span><a href=\"https:\/\/www.mdpi.com\/2076-3425\/11\/7\/835\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Eliciting and recording event related potentials (ERPs) in behaviorally unresponsive populations: a reflective commentary on critical factors<\/span><\/a><span style=\"font-weight: 400;\">\u201d.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Second, we adapted a common ERP task to the local context of Montreal, Canada, where French and English are the dominant languages.\u00a0 The N400 ERP is a response evoked by a semantic incongruence (e.g. \u201cHe takes his coffee with cream and socks\u201d).\u00a0 The presence of the N400 in a behaviourally unresponsive individual indicates a high level of consciousness and intact language comprehension abilities.\u00a0 While a normed version of English N400 sentences exist, there was no equivalent in Canadian French, thus excluding over half of the potential disorders of consciousness patients in Quebec.\u00a0 In collaboration with Nancy Azevdo and Dr. Eva Kehayia, we created a Canadian French N400 sentence stimulus set.\u00a0 We normed the sentences in a group of 200 adults, and demonstrated that they were able to generate canonical N400 ERPs in a set of 33 adults across three different age groups.\u00a0\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Please contact the BIAPT lab if you would like access to the Canadian French N400 sentence stimulus set.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Auditory event-related potentials (ERPs) have often been used to assess the level of consciousness of behaviourally unresponsive individuals.\u00a0 In this set of research projects, we first published a retrospective commentary of the critical factors to be considered when designing paradigms to evoke ERPs in patients in a disorder of consciousness.\u00a0 We demonstrated that 1) the [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":50216,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[53,50],"tags":[],"class_list":["post-50107","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-assessing-consciousness-past","category-past-projects"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/posts\/50107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/comments?post=50107"}],"version-history":[{"count":2,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/posts\/50107\/revisions"}],"predecessor-version":[{"id":50192,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/posts\/50107\/revisions\/50192"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/media\/50216"}],"wp:attachment":[{"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/media?parent=50107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/categories?post=50107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.moraeslab.com\/biapt\/wp-json\/wp\/v2\/tags?post=50107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}